• Lucy

What Drugs Should You Not Take With CBD?

Taking some capsules that shouldn’t mix could spell doom, and it’s the same story with CBD.

Most medical practitioners don’t fail to ask what kind of meds you’re on before prescribing a dosage. Doctors do this to avoid any adverse interaction between their prescription and your current meds.

It is imperative to let your doctor know what you’re taking, even if it’s your first CBD use. Don’t think because CBD is relatively new and natural, it can’t cause any harm. You could be sent reeling from a wrong mix when it hits your system.

With all these laid out, it’s essential to find out how CBD capsules and oils affect your system.

At Ohbeyond.com, we remain committed to making the most of your CBD journey. And with the information this post possesses, you can be sure of improved CBD use in each dosage.

Why CBD Use Affects Some Drug Types

CBD use affects many drug types based on its adverse interaction with some body metabolisms. The CYP450 enzyme sub-class is responsible for more than half of biochemical processes in our stomachs.

CBD could interfere with some enzymes in this sub-class and cause medications to break down much slower. Slower metabolism could mean your prescription won’t achieve its desired effects.

What Types of Drugs Should I Not Take With CBD?

  • Sulfonylureas

  • Steroids

  • Prokinetics

  • PPIs

  • Oral hypoglycemic agents

  • NSAIDs

  • HMG CoA reductase inhibitors

  • HIV antivirals

  • Calcium channel blockers

  • Beta blockers

  • Benzodiazepines

  • Antipsychotics

  • Antihistamines

  • Anti-epileptics

  • Antidepressants

  • Antibiotics

  • Antiarrhythmics

  • Angiotensin II blockers

  • Anesthetics

How CBD May Interact with The Most Commonly Prescribed Prescription Drugs

  • Amlodipine – efficacy reduction, side effect extension, medication tainting

  • Amoxicillin – possible effects currently unknown

  • Azithromycin – possible effects currently unknown

  • Hydrochlorothiazide – possible effects currently unknown

  • Levothyroxine – possible CBD product effect inhibitor

  • Lipitor – possible toxic effect on meds, efficacy reduction, side effect extension

  • Lisinopril – possible effects currently unknown

  • Metformin – could inhibit CBD metabolism

  • Simvastatin – side effect extension, possible toxic effect on meds, efficacy reduction,

  • Vicodin – no known side effects

Does How I Take CBD Make a Difference?

Since its legalization, CBD is now available in a slew of forms. Some of these methods include;

Edible CBD

Gummies, baked goods, and other edibles rank as very popular CBD options, especially among young users and pet owners. Edible CBD is actually the slowest when it comes to decomposition rate in our digestive system.

Nonetheless, edible CBDs could take within half an hour to a full hour to kick in.


CBD ingested as capsules has similar decomposition properties like its edible options. Capsules offer precise dosages as a plus and could take up to one hour for full effects to set in.


CBDs available as drinks could kick in within an hour based on its direct gut absorption potential.

Vape CBD

Vaporized CBD is one of the fastest and most popular methods of ingestion. Since vapor moves through the bloodstream in moments, there’s a high chance of feeling effects in less than fifteen minutes.

Topical CBD

Several creams, lotions, and moisturizers come with CBD for direct skincare. Most topical CBD products focus on reducing inflammation. CBD in the cream acts as an inflammation cytokine inhibitor for soothing skin relief.

It could take at least half an hour for topical CBDs to show signs of effectiveness.


Many tinctures are CBD extracts suspensions in pure alcohol or other liquid. CBD tinctures are usually ingested sublingually (underneath the tongue) and absorb through inner linings of our lower mouth region.

Tinctures could also mix into beverages and consumed directly to flow into the digestive system.

A precise content of CBD is available in most suspensions, and higher content results in improved efficacy.

Using tinctures means it could take less than thirty minutes for effects to kick in. Also, it could take several hours for this suspension’s effect to wear out.

Final Word

With all the pomp surrounding CBD, it still has a long way to go in the scientific world. Several studies, including its reactions with other medications, are underway.

But it’s noteworthy that CBD enjoys wide acceptance as a harmless substance. Legislature approving CBD for medicinal and recreational use increases every other year. All these gives CBD a pride of place among several therapeutic products.

Sparkling recommendations aside, it is still essential to consider how CBD interacts with our body and other medication.

It is a possibility for CBD to boost or cancel out the effects of other meds you’re on. Consider checking out how CBD interacts with your current meds. And be sure to balance out your prescribed meds before ingesting any more CBD.

Also, consider checking out with your doctor whenever there’s a new prescription. Your health could take a hit if you don’t use CBD the right way.